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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIM2 All Species: 26.97
Human Site: S440 Identified Species: 49.44
UniProt: Q9C040 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C040 NP_001123539.1 744 81530 S440 G V K R R V K S P G S G H V K
Chimpanzee Pan troglodytes Q1XHU0 518 59727 D235 E N A A H L G D K R R D L A H
Rhesus Macaque Macaca mulatta XP_001086516 744 81496 S440 G V K R R V K S P G S G H V K
Dog Lupus familis XP_534038 744 80763 S437 D V K R R V K S P G G P G S H
Cat Felis silvestris
Mouse Mus musculus Q9ESN6 744 81427 S440 G V K R R V K S P G S G H V K
Rat Rattus norvegicus O70277 744 80777 S437 D V K R R V K S P G G P G S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514346 744 81576 S440 G V K R R V K S P G S G H V K
Chicken Gallus gallus Q1PRL4 876 94170 D550 L F G A D V S D Q Q N G T Y L
Frog Xenopus laevis NP_001085492 748 81469 S440 G V K R R V K S P G S S H V K
Zebra Danio Brachydanio rerio NP_001014393 744 81213 S440 V D K K R L K S P G N S H V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MQJ9 1037 110348 L549 G G P T G M S L T S N G H G K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U489 1147 124214 N800 I E G S Y T L N I L V K G T P
Sea Urchin Strong. purpuratus XP_796849 747 81758 R444 P S G K I P V R T S V R Q K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.4 97.8 67.1 N.A. 99.1 66.6 N.A. 97.9 24.7 91.7 80.1 N.A. 23.3 N.A. 21.3 53.8
Protein Similarity: 100 35.6 98.7 82.3 N.A. 99.7 81.7 N.A. 99.4 40 96.7 90.7 N.A. 36.7 N.A. 35.3 72
P-Site Identity: 100 0 100 60 N.A. 100 60 N.A. 100 13.3 93.3 60 N.A. 26.6 N.A. 0 0
P-Site Similarity: 100 6.6 100 60 N.A. 100 60 N.A. 100 20 93.3 80 N.A. 40 N.A. 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 16 0 0 0 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 8 0 0 8 0 0 16 0 0 0 8 0 0 0 % D
% Glu: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 47 8 24 0 8 0 8 0 0 62 16 47 24 8 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 54 0 24 % H
% Ile: 8 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 62 16 0 0 62 0 8 0 0 8 0 8 54 % K
% Leu: 8 0 0 0 0 16 8 8 0 8 0 0 8 0 8 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 8 0 0 24 0 0 0 0 % N
% Pro: 8 0 8 0 0 8 0 0 62 0 0 16 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 8 8 0 0 8 0 0 % Q
% Arg: 0 0 0 54 62 0 0 8 0 8 8 8 0 0 0 % R
% Ser: 0 8 0 8 0 0 16 62 0 16 39 16 0 16 0 % S
% Thr: 0 0 0 8 0 8 0 0 16 0 0 0 8 8 0 % T
% Val: 8 54 0 0 0 62 8 0 0 0 16 0 0 47 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _